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Stimulant medications like amphetamine and methylphenidate work by blocking dopamine reuptake, increasing synaptic dopamine availability in these exact regions

Adherence remains an important challenge, but it may not be sufficient for critical disease activity or advanced fibrosis (101)

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In case of emergencies, stock up on naloxone

Absorption from the abdominal subcutaneous tissue tends to be slightly faster than from the thigh, though the difference is not clinically meaningful for a long-acting medication like tirzepatide