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Semaglutide may be appropriate for patients who: Our weight loss clinic will determine if semaglutide is appropriate for your needs through a comprehensive medical evaluation at your first visit, which includes a review of your health history, current medications, and body composition

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Contact your healthcare provider promptly if GI side effects are persistent, severe, or accompanied by a significant drop in urination

The drug helps regulate appetite by signaling fullness to the brain, slowing digestion, and reducing hunger between meals

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Although lifestyle changes are the first line of treatment for obesity, even the most rigorous lifestyle changes typically only produce a 510% weight loss and maintaining weight over time is difficult due to compensatory physiological processes that increase appetite and decrease energy expenditure [134]