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medRxiv [Preprint] (2020), 2020.09.01.20185850

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Mounjaro (tirzepatide) is a once-weekly subcutaneous injection that activates two gut hormone receptors at once, GIP and GLP-1, to suppress appetite, slow gastric emptying, improve insulin sensitivity, and increase energy use

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It represents the closest currently approved pharmacological relative to retatrutide in terms of mechanism

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As most GLP-1s require prior authorization for insurance coverage, it is likely you will need it

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Some genetic profiles trigger stronger early satiety, while others show different nausea or energy patterns

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