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Patients with certain genetic variants may have a higher propensity for gallstone formation, elevated triglycerides, or pancreatic sensitivityall factors that increase pancreatitis risk

doi: 10.1016/j.heliyon.2024.e41440 85 TangWChenBLeungGKKiangKM
They usually lessen over time as your body gets used to the medication

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This is not a trivial consideration