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Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, Thom LH, Buerk DG

One minute your back feels a little tight, and the next youve got sharp, shooting pain running from your lower back all the way down your leg

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Philippe J

The beta-cell mass plays a critical role in obesity duration, in which pancreatic fat contents increase and are suggested to cause beta-cell dysfunction, resulting in a worsening glycemic control [2]

Gatekeeping strategies for avoiding false-positive results in clinical trials with many comparisons

Subtle conformational dynamics allow the C-terminus of GLP-1 to access the ECD binding site, and the ligand binding triggers further dissociation of the ECD from the TMD allowing the N-terminus of GLP-1 to enter the orthosteric pocket in the TMD and activate the receptor