fda label semaglutide naion warning 2025 use linked with increased risk for in patients with diabetes Your diabetic patient on semaglutide

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When to Avoid Semaglutide and Alternative Options A small group of patients should not take semaglutide, including those with personal or family history of medullary thyroid cancer and people with severe retinopathy from uncontrolled diabetes

Studies show patients on GLP-1 agonists consume 25-40% fewer calories daily, which means vitamin and mineral intake drops proportionally unless you intentionally adjust your diet composition

Furthermore, semaglutide improved adverse cardiac Remodelling, concomitant with substantial weight loss 2836

Understanding these differences is essential for accurate patient education and appropriate therapeutic expectations

Many patients hold a step longer for tolerability, and the optional Ozempic 2.0 mg extension is added only when a clinician judges it clinically appropriate