amgen glp 1 and Pfizer's Monthly GLP-1s Compared | Ahmad Bahareth, MD posted on the topic The expanding benefits of GLP-1

This effect is especially notable with SGLT1i

Physiol Rev 97:721766

By accelerating fat oxidation in the liver, it may help raise the body's metabolic output to enhance overall calorie expenditure

10.2165/00002018-200629100-00005 4 AlsaadounA

Considerable interest exists in identifying effects of these drugs beyond glucose-lowering, possibly resulting in improved macrovascular and microvascular outcomes, including in diabetic kidney disease

Within the pancreas, GIP and GLP1 together promote cell proliferation and inhibit apoptosis, thereby expanding pancreatic cell mass, while GIP enhances postprandial glucagon response and GLP1 suppresses it