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In randomized trials, GLP-1s produce placebo-adjusted weight reduction of 5% to 18% among individuals with obesity or overweight and weight-related complications
So here you can see sort of a timeline of weight loss drugs

So going back to the subtopic of microdosing, I think generally you and I are talking about the same thing when we just start talking about a lower than one milligram per week or 2.5mg per week dose

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This weight-regulating hormone signals fullness to the brain, delays stomach emptying and lowers blood sugar, says Rekha Kumar, chief medical officer at the medically-assisted weight loss program, Found, and practicing endocrinologist in New York City
For clients who feel isolated in their weight loss efforts, the coaching and community structure can be the difference that keeps them going