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Several preclinical studies have shown that lanifibranor has both antifibrotic and positive metabolic effects

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People with severe or persistent symptoms should seek medical care rather than stopping or changing medication without professional guidance

17,18 However, a study directly comparing different modalities of exercise found that exercise programs including resistance training may be particularly effective at reducing the loss of thigh skeletal muscle volume during weight loss

Third, although the beneficial effects of bezafibrate in db/db mice were associated with improvements in islet architecture and beta cell mass, whether normalisation of circulating lipid levels also improved incretin signalling in non-beta cells (for example, in the brain) was not directly examined

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