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Efficacy and safety of once weekly semaglutide 24 mg for weight management in a predominantly East Asian population with overweight or obesity (STEP 7): a double-blind, multicentre, randomised controlled trial

The mechanism of action of Semaglutide is rooted in its structural similarity to the naturally occurring incretin hormone GLP-1, which is integral to glucose homeostasis
Studies with sotagliflozin did not include patients with an eGFR less than 25 or on dialysis and in these studies, sotagliflozin was discontinued if eGFR fell below 15 or chronic dialysis was initiated

Avoid fatty foods immediately beforehand and never donate on an empty stomach, as this increases the risk of hypoglycaemia and fainting

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