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Introduction Drug shortages of long-acting GLP-1 receptor agonists and dual GLP-1/GIP receptor agonist have emerged unexpectedly and persisted through the first quarter of 2023

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The healthcare infrastructure is well-developed, and there is a high level of patient and doctor awareness about advanced treatments

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Though both conditions occur within the distribution of the mesenteric artery, mesenteric ischemia is a much more serious and sometimes life-threatening condition that affects the small bowel

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A key strategy being deployed by drug developers to improve side effect profiles is titration

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Bottom Line The largest patient-voice analysis of GLP-1 drugs to date confirms that gastrointestinal side effects dominate the real-world experience and surfaces two underrecognized signal clusters: reproductive and temperature symptoms

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Watts, A

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