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The current ASA guidelines are based on expert consensus rather than high-quality clinical evidence, and may not adequately address the perioperative risks posed by these medications

Finally, GLP-1s affect both insulin and glucagon release

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Short-chain fatty acids (SCFAs) produced by gut bacteria through activation of the G protein-coupled free fatty acid receptors FFAR2 (GPR43) and FFAR3 (GPR41) induce GLP-1 Secretion [159]

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