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A press release from the U.S

Pharmacokinetics and pharmacodynamics of retatrutide in healthy adults Urva S, Coskun T, Loh MT, et al

CANVAS demonstrated a 14% reduction in MACE in patients with T2DM and a high cardiovascular risk ( 4.1.2 Cardiovascular results in studies aimed at CVD The CREDENCE clinical trial evaluated the effects of canagliflozin (100 mg daily) versus placebo in 4,401 patients with T2DM and CKD

[1] [7] For patients taking warfarin or other coumarin anticoagulants (sometimes used in antiphospholipid syndrome), more frequent INR monitoring is recommended when starting Wegovy