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According to Houston plastic surgeon Kristy L

How Mounjaro works Mounjaro works by mimicking two hormones, instead of one: Like Wegovy, it mimics the hormone GLP-1 It also mimics a second hormone called GIP (glucose-dependent insulinotropic polypeptide) This dual-action likely explains why Mounjaro produces greater average weight loss in clinical trials at standard doses

Less serious side effects may also occur, including nausea, vomiting, diarrhea and constipation, according to Harvard Health

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44 Although cost-effectiveness analyses favor tirzepatide, actual patient access depends on formulary placement, insurance coverage, and copay structures