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For once-weekly subcutaneous administration of semaglutide 1.0 mg, change from baseline in mean body weight after 12 weeks was 5.0 kg vs

These medications produce significantly larger average weight changes in high-quality trials, but they are prescription medicines with different risk profiles and routes of administration

The FDA prescribing information explicitly states that semaglutide must not be frozen

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Liraglutide showed a decline in monthly prescriptions throughout the study period, from 0.33 million to 0.11 million
