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The evidence so far suggests that GLP-1s appear to modulate reward pathways in the brain that shape craving and compulsive drug use

It tanks your metabolism and sets you up for rapid weight regain once you come off the medication

Trulicity sales in 2015 reached $248.7 million and continued to climb to $925.5 million in 2016 and to $2030 million in 2017, taking significant market share away from Victoza (Figure 7, Table 5) [187-189]

While the medications are made by the same company, there is one big difference

After completing his PhD in 1964, Brown spent the following year, supported by a Wellcome Foundation Travel Award, with Donal Magee, a Scottish born pharmacologist and surgeon based at the University of Washington

And as soon as a person stops taking them, they often regain lost weight