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Ghrelin signaling has increasingly been recognized as a key regulator of obesity, insulin resistance and diabetes

That kind of inconsistency makes research planning impossible

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Diabetes Obes Metab 2021;23:938-49.PubMed 170

In contrast to ghrelin, no cluster survived correction for multiple comparisons which could be due to the lower number of eligible contrasts
Sipping water regularly may be more effective than consuming large amounts at once
