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Cignas announcement to phase out rebates in favor of upfront discounts is an important signal that the system needs change

NICE guidance supports using one incretin-based therapy at a time, and if Mounjaro is initiated, Januvia is typically discontinued

This disruption is referred to as type 3 diabetes and is characterized by neuroinflammation, cognitive deficits, and amyloid pathology, which are common to both DM and AD

B12 supplementation is particularly important because reduced food intake naturally reduces B12 consumption, and B12 deficiency causes fatigue that further reduces physical activity