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Description
Collectively, these modifications prolong the half-life of Tirzepatide to approximately 5 days (FDA package insert)
(2013) GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice
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Mechanistically, these effects are coherent
Available from: [DOI] [PubMed] 15.Chu GX, Ling Q, Guo ZG
