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The authors discuss the preclinical literature and emerging clinical evidence that support the rationale for investigating the use of glucagon-like peptide-1 receptor agonists to prevent and treat several neurodegenerative diseases of aging, with a focus on Alzheimers disease.

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The analysis showed significantly greater WL in the GLP-1RAs group compared to placebo (SMD=0.82, 95% CI 0.23 to 1.42)

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