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The classification is more important information for doctors than for patients

Regular monitoring ensures hormone levels remain within optimal ranges

All three drugs exhibit significant weight loss effects in patients with obesity or who are overweight with comorbidities in various clinical trials

it is available for wellness, anti-aging, and performance enhancement

Table 2 below depicts Medicare Part Ds national gross spending on GLP-1s that are FDA-approved for treating T2D

Furthermore, its short half-life of less than 3 h (Min et al., 2025) necessitates twice-daily injections to maintain efficacy, which can be a limiting factor for long-term patient adherence