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Key takeaways Mounjaro (tirzepatide) is FDA approved for Type 2 diabetes but is often prescribed off-label for weight loss

Endocrinology (1998) 139(10):442831

No changes in LDL-C and HbA1c were observed, suggesting that GLP-1RAs affect atherosclerosis through an anti-inflammatory mechanism (Punjabi et al

Widespread Issues: A skin rash away from the injection site, severe itching over the whole body, or hives

Most positive berberine studies use 900-1500mg daily divided into 2-3 doses

It was launched in 2014 by the NIHs National Institute of Allergy and Infectious Diseases (NIAID)
