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Do proton pump inhibitors interfere with oral GLP-1 medications

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Therefore, it is recommendable to decrease the sulphonylurea or insulin dose in patients on sulphonylurea or insulin therapy who start a GLP-1 receptor agonist to reduce the risk of hypoglycemic episodes [137]
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If you are researching retatrutide dosing , follow the same conservative approach as tirzepatide until official guidelines are published