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Tirzepatide and injectable semaglutide were associated with the greatest weight loss after a year of treatment among several GLP-1 receptor agonists, a recent study showed.“Despite being the most recent medication approved for weight loss, tirzepatide [Zepbound, Eli Lilly] showed the greatest weight loss among the GLP-1 medications studied,&rdquo

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Further studies in models more closely reflecting type 2 diabetes are warranted to clarify the underlying mechanisms and translational relevance

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