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Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins

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The term natural is often misunderstood

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In this article, we review the latest research to highlight when these medications might offer the greatest benefit for patients with substance use disorders.

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