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Higher-risk patients may require temporary pausing: daily injections 24 hours before, weekly injections 7 days before surgery

Yuan S, Larsson SC

The incidence of selected gastrointestinal adverse reactions in patients treated with Januvia was as follows: abdominal pain (Januvia 100 mg, 2.3%

They slow gastric emptying, reduce appetite, and help regulate blood sugar

When it does occur, it's usually related to dry mouth, dietary changes, or ketosis during weight lossall of which are manageable with hydration and oral hygiene adjustments

Improved absorption rates result in significantly decreased inter-individual and intra-individual variability with improvement in glycemic control and reduced hypoglycemia risk