dpp 4 and glp 1 together DPP4 degrade the GLP1 incretion, which leads to suppression of the A Comprehensive Review on Dipeptidyl

Diabetes Care 37, 27232730

concerning) How dosing increases gradually over weeks What to do if you experience side effects You'll learn Week 1-2: Possible nausea, loss of appetite (normal) Week 3-4: Body adjusts, side effects usually improve Week 5-8: Appetite suppression peaks, weight loss increases Month 2+: Steady, consistent weight loss Step 4: Medication Safety Screening (5 minutes) The physician will ask Are you pregnant or trying to become pregnant?" (GLP-1 isn't recommended) Any history of thyroid cancer or medullary thyroid cancer?" (Important safety issue) Gallbladder disease, pancreatitis, or kidney problems?" (Need to monitor) Taking any other weight loss medications?" (Can't mix) Allergic to any medications?" (Especially previous allergies to injectables) Why: GLP-1 is safe, but its not appropriate for everyone

Some drugs dont mix well with GLP-1 antagonists

Clinical studies (in both obesity and type 2 diabetes) consistently show that GLP-1 RA treatment leads to less hunger, increased satiety, and spontaneous decreases in daily caloric consumption (Zheng et al., 2024)

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By working with your bodys natural hormones, it helps regulate blood sugar levels and slow digestion, allowing you to feel full longer