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Recommendations to standardise the methodology for scintigraphy include ensuring blood glucose concentrations are 20mmHg) fall in blood pressure after meals (postprandial hypotension) occurs in up to 40% of individuals with long-standing, complicated diabetes (more common than orthostatic hypotension), and is associated with more rapid gastric emptying [35]

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase

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Of particular concern for patients with diabetes, berberine may potentiate the glucose-lowering effects of antidiabetic medications, including insulin, sulfonylureas, and meglitinides, potentially increasing hypoglycemia risk

First-line therapies, including metformin, sodium-glucose cotransporter-2 inhibitors (SGLT-2i), and Glucagon-like peptide-1 (GLP-1) receptor agonists, are selected according to patient-specific risk factors

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