obesity drug news today glp-1 World Health Organization recommends drugs for Upcoming wave of hormone-based therapies
Description
This is the first study to establish a causal relationship between genetically proxied GLP-1RAs and arrhythmias using MR analysis
doi: 10.1210/jcem.80.3.7883856 33 DruckerDJNauckMA
The most common cardiovascular (CV) manifestations in patients with type 2 diabetes are heart failure (HF), stable angina, nonfatal myocardial infarction (MI), peripheral arterial disease and ischemic stroke [2,3,4] which accounts for 60% of their deaths [5]
Crucially, they trigger insulin release only when glucose is already present in the bloodstream, minimizing the risk of dangerous hypoglycemia seen with some older diabetes drugs
JACC 65(20):21592169 Lavie CJ, Pandey A, Lau DH, Alpert MA, Sanders P (2017) Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: effects of weight loss and exercise
doi: 10.1172/JCI72434 [DOI] [PMC free article] [PubMed] [Google Scholar] 143
