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At 72 weeks, mean weight loss was 15.0% (5mg), 19.5% (10mg), and 22.5% (15mg) versus 3.1% with placebo

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Because GLP-1 medications slow gastric emptying, they can affect the absorption of orally administered drugs particularly those with narrow therapeutic indices

The upcoming SURMOUNT-MAINTAIN trial, expected to report results around mid-2026, will specifically compare the 5 mg maintenance dose against higher doses for weight maintenance after initial loss

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