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This review explores the safety, efficacy, and clinical outcomes of these interventions on weight reduction, hormonal balance, menstrual regularity, and metabolic outcomes in both obese and non-obese women with PCOS.

Control Appetite and Curb Cravings

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Emerging research suggests GLP-1 receptor agonists may help manage these symptoms by targeting the same hunger pathways disrupted in PWS

Off-label SGLT2 inhibitors increase the risk of euglycemic diabetic ketoacidosis

But despite widespread use of these drugs by perimenopausal women, research has largely ignored the unique risks and potential opportunities for optimizing health that GLP-1s may pose for this population.