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The combination of reduced food intake (which normally provides water content), increased metabolic demand, and the medication's diuretic effects can compound skin dryness

The short answer is yes, and there is really solid research that backs that up

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Interestingly, a comparison of acute metabolic responses with the chronic profiles at the end of the treatment period strongly suggests that while the different GLP1-based agonists may share primary mechanisms of action, the durability and efficiency of their long-term metabolic responses differ, with clear superiority for the GLP1/E compound

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However, they are not suitable for everyone