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Close Monitoring: Pay close attention to any changes in your mood, anxiety levels, sleep patterns, and overall mental well-being after starting or adjusting the dosage of a GLP-1 inhibitor

Your provider must document BMI, relevant comorbidities (diabetes, hypertension, cardiovascular markers), and why GLP-1 therapy aligns with clinical guidelines

Contact your GP or prescribing clinician if you experience complete absence of periods (amenorrhoea) for three consecutive months or longer, particularly if you are under 45 years of age and this represents a change from your usual pattern

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People who have excess toxins known as ketones in the blood or urine a life-threatening condition known as diabetic ketoacidosis should not take Januvia or Janumet

To evaluate the information content generated by the sequence design process, we calculated the entropy across each set of designed sequences, and the relative entropy (KullbackLeibler divergence, KL) between the distribution of amino acids at each sequence position estimated for the model-designed samples, and the training data