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It enhances insulin secretion from pancreatic -cells, and decreases glucagon release from pancreatic -cells [16]

(1994) Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells: its structure and functional properties

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Intensive blood- glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

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Exendin-4 inhibits the reduction of LTP in the brain of a mouse fed a high-fat diet 138 and significantly increased the phosphorylation level of CREB and the expression level of BDNF