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Detailed statistics are in Supplementary Table 1
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However, they have different FDA-approved uses and insurance coverage
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Epac2 interaction with Rim2 and Piccolo is crucial for cAMP-induced Ca 2+ -dependent insulin secretion and is not blocked by inhibition of PKA [493,512,513]
Mering and Minkowski's findings encouraged Gustave-douard Laguesse, a French histologist and pathologist, to theorise in 1893 that the pancreatic islets described by Langerhans produced an endocrine secretion (Hoet)
