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Body weight affects the peak concentration and overall exposure, but not the half-life itself

Tirzepatide enhanced functional ability, quality of life and reduced the risk of worsening HF events in obese patients with HFpEF, with benefits observed even among those with chronic kidney disease, according to the SUMMIT trial

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10.12688/f1000research.157194.2 59 SterneJ

The medication can tolerate brief periods at room temperature, but extended heat exposure degrades the active compound