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Paeschke A, Erben U, Kredel LI, Kuhl AA, Siegmund B

This physiological shift creates an environment where healthy eating patterns become easier to maintain

A well-studied GIPR missense variant, E354Q (rs1800437), is associated with reduced BMI in large-scale GWAS and Mendelian randomization analyses

The mechanism for action for regulating glucose metabolism of OXM remains elusive but might involve a similar pathway to GLP-1 since it activates the same receptor, although OXM is still able to improve glucose metabolism in mice lacking GLP-1R 211

doi: 10.1152/ajpregu.00444.2015, 96 Matikainen-AnkneyB

Right upper quadrant pain, fever, or yellowing of the skin/eyes could indicate gallbladder disease