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CMS has said it will monitor plans to make sure they do not shift these prescriptions to the Bridge to offload cost

Effects of the novel (Pro3)GIP antagonist and exendin(939)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin

This demonstrates that hormones secreted from the gastrointestinal tract during oral glucose administration are involved in promoting pancreatic insulin secretion

Source: frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1548346/full

GLP-1 medication use can lead to undereating, nutrient deficiencies, and associated microbiome changes, which can affect hormone levels, ovulation, and deplete nutrient stores that are important during pregnancy