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5.3 Cost and Access Are Not Mechanism Problems The most common reason patients discontinue GLP-1 therapy is cost

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Individuals participating in programs like Tyde Wellness report an average body weight reduction of 15% after 68 weeks, with many achieving weight loss exceeding 20-25% within a year

These included isolated cases of pancreatitis, prolonged QT syndrome (associated with concomitant medications), and transient elevations in liver enzymes