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Review Article OPEN ACCESS Lun-Gen Lu * Author information Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently a pressing public health issue associated with adverse outcomes such as cirrhosis, malignancy, transplantation, and mortality

The centrality hypothesis proposes that hyperglycemia is associated with hippocampal atrophy and a hypothetical decrease in hypothalamic inhibition of the hippocampus

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Improving insulin sensitivity: By improving insulin function, these medications can also assist in better blood sugar control, which is especially important for individuals with Type 2 diabetes or insulin resistance

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Its presence in formulas targeting appetite reflects research on the connection between blood glucose stability and craving behavior - specifically, the carbohydrate and sugar cravings that reliably follow blood sugar instability