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In this paper, the authors describe the energy state-dependent regulation of the PVNGLP-1R to DVC circuit, resulting in altered food intake and metabolic health, mediated by GLP-1 receptor signalling.

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Kristin Louden, an Obesity Medicine nurse practitioner at Cleveland Clinic, discusses the truth and myths of GLP-1 weight loss medications.

Tirzepatide Microdose delivers the dual GLP-1 and GIP action of tirzepatide at a lower starting dose a gentler introduction for those new to dual-action GLP-1+GIP therapy.