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Indeed, while confusing these two lesion types may have been justified back in 2002, when a letter to the editor published in Diabetes Care proposed a three-stage classification for insulin-related LD despite little being admittedly known about the nature and causes of described phenomena [3, 7, 23]

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Data representative of two independent experiments with Tm values calculated as the arithmetic mean and the standard deviation of the mean

In laboratory research settings, GLP-1 has been investigated as a reference peptide for studying incretin receptor signaling and insulin-response pathways in vitro