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N Engl J Med 390(13):11761185

65 Zhu et al 66 reported a unique case where a patient developed a painful nodule on the left lower quadrant of her abdomen in response to exenatide extended-release injections

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Regulatory Consequence: The FDA concluded that the "reliability of data is fundamentally compromised".5 The remediation required a "comprehensive investigation into the extent of the inaccuracies," involving interviews with current and former employees to uncover the "nature, scope, and root cause" of the data integrity culture.5 2.6 Annovex Pharma Inc

doi:10.1016/j.dsx.2025.103212

These findings support a meaningful role for these medications in blood pressure management in overweight and obesity and underscore the need for targeted mechanistic and clinical studies to calculate weight-dependent and weight-independent effects, they added