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Extensive in vitro pharmacological characterization of the active peptides revealed that P5 displayed comparable efficacy to the endogenous ligand GLP-1 and its analogue Ex4 with regards to G-protein signalling

a small study compared dapagliflozin and teneligliptin in patients with MASLD and found improvements in transaminases and a reduction in body fat only in the group treated with dapagliflozin 49

J Gastroenterol Hepatol 39(2):353359 Singh S, Boland BS, Jess T, Moore AA (2023) Management of inflammatory bowel diseases in older adults

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This protective effect results from the upregulation of FOXO3 ( 5 Systemic regulation via gut-liver axis Intestinal microbiota is a complex and multifunctional system comprising bacteria, viruses, and other microorganisms