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4, the three most frequently reported SOC categories were "Gastrointestinal disorders," "General disorders and administration site conditions," and "Investigations." Notably, while "Injury, poisoning, and procedural complications" and "Nervous system disorders" demonstrated higher reporting frequencies compared to other SOCs, these associations did not reach statistical significance in our analysis, suggesting potential reporting bias or confounding factors that warrant further investigation

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Systemic sclerosis

Baseline portal vein levels of active GLP-1 are 10 pmol/l and increase up to 40 pmol/l upon treatment with neuromedin C [241]

Am J Gastroenterol 1986

Chapman I, Parker B, Doran S, et al