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It stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it only triggers insulin release when blood glucose levels are elevated

Wootten D, Reynolds CA, Smith KJ, Mobarec JC, Koole C, Savage EE, et al

Historically, each GLP-1 dollar was split roughly like this: Pharma (Lilly/Novo): ~60% PBMs, insurers, wholesalers, pharmacies: up to 40% That 40% is not value-added

They delay gastric emptying, slow intestinal transit, and alter the hormonal signaling that coordinates digestion

Campbell Jonathan E, Drucker DJ

With meals: This timing works well for prebiotic fibers like acacia or PHGG