are glp 1 safe in pregnancy while taking GLP-1 injections? GLP-1s and Pregnancy: Safety, Risks,
Description
There are ongoing studies for these uses, but early data are weak and the risks are unknown

Because you need a BMI 40 (or 35 with diabetes/sleep apnea), documented

Nonnutritive agonists of sweet taste receptors do increase GLP-1 levels and mice null for one such sweet taste receptor, -gustducin, have reduced GLP-1 responses to an oral glucose load (102)

This effect has been observed in several cardiovascular outcome clinical trials

The first is semaglutide: Ozempic is the lower-dose version approved for type 2 diabetes, and Wegovy is the higher-dose version approved for obesity

GLP-1 agonists reduce systolic blood pressure by 3-5 mmHg, improve lipid profiles, and lower progression to cardiovascular events by 26% in high-risk type 2 diabetes patientseffects that appear independent of weight reduction alone
