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doi: 10.1016/j.jacc.2025.05.024 [DOI] [PubMed] [Google Scholar] 2
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placebo on cardiovascular and renal outcomes (macroalbuminuria) was similar in the absence and presence of baseline SGLT-2 inhibitors

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To date, several small molecule DPP-4 inhibitors (vildagliptin, sitagliptin, saxagliptin, lina-gliptin, and alogliptin) have been used as treatments for type 2 diabetes to improve glucose tolerance
Its worth noting that cardiovascular mortality over two years was 50% to 70% higher in patients using sulfonylureas compared to those on metformin, according to research
