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So about that research: The vast majority of the studies done on Protandim have been done on rats and on cells in lab dishes

doi: 10.1016/0306-4522(93)90191-h 33 VizueteMLTraiffortEBouthenetMLRuatMSouilETardivel-LacombeJet al

Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism

Discontinuation rates remain below 5%

Readers comparing investigational and approved options should keep the distinction clear

Beneficial effects on kidney during treatment with sodium-glucose cotransporter 2 inhibitors: Proposed role of ketone utilization
