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References Are GLP-1 and GIP injections effective for quitting smoking

Then came tirzepatide, a dual agonist that targets both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

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Tirzepatide has been granted FDA approval for treatment of type 2 diabetes based primarily on a series of trials known as SURPASS

One theory is that Retatrutides stimulation of GLP-1, GIP, and glucagon receptors may interact with the autonomic nervous system, shifting the balance towards slightly increased sympathetic activity

Proc Natl Acad Sci U S A 105: 66146619, 2008